First Unprovoked VTE, Cause for Lifelong Blood Thinners?

Today's episode is a very complicated topic without clear cut benefits. Expert opinions and modeling data to address a dangerous and serious topic. Let's look at 2 sources: a new study from the Annals of Internal Medicine and an expert opinion from Uptodate.

 

https://www.uptodate.com/contents/selecting-adult-patients-with-lower-extremity-deep-venous-thrombosis-and-pulmonary-embolism-for-indefinite-anticoagulation?search=unprovoked%20dvt§ionRank=1&usage_type=default&anchor=H648618&source=machineLearning&selectedTitle=1~150&display_rank=1#H648618

 

vs.

 

https://pubmed.ncbi.nlm.nih.gov/37364263/

Indefinite Anticoagulant Therapy for First Unprovoked Venous Thromboembolism : A Cost-Effectiveness Study

Faizan Khan ¹, Doug Coyle ², Kednapa Thavorn ³, Sasha van Katwyk ⁴, Tobias Tritschler ⁵, Brian Hutton ⁶, Grégoire Le Gal ⁷, Marc A Rodger ⁸, Dean A Fergusson ⁹